About OligoPool.com
Free, accurate tools for oligonucleotide design, built for researchers by a developer.
Mission
OligoPool.com provides free, scientifically accurate calculation tools for oligonucleotide design. All tools are based on published, peer-reviewed methods—no proprietary algorithms, no black boxes.
As an individual developer, I built this site to address a simple problem: commercial oligo design tools are often expensive, require subscriptions, or collect user data. Academic alternatives are frequently outdated or difficult to use. This project aims to fill that gap.
Core Principles
100% Free
No paywalls, no subscriptions, no "premium" features. All tools freely available forever. Funded by the developer, not by user data or advertising.
Privacy First
All calculations run in your browser. Sequences never transmitted to any server. We use minimal analytics (Google Analytics) for website improvement only—no tracking of your research data. Verify via browser developer tools.
Scientifically Accurate
Methods based on published literature (SantaLucia 1998, Owczarzy 2008, etc.). Transparent algorithms, reproducible results. Scientific rigor over marketing claims.
Open & Transparent
Calculation methods documented. Source code available for review upon request. Found a bug? Report it. Have a suggestion? Contact me directly.
Technical Implementation
Built with modern web technologies: Next.js, React, TypeScript, Tailwind CSS. Static site generation ensures fast loading and works offline after initial visit. All calculations implemented in client-side TypeScript—no backend required.
Hosted on Cloudflare Pages for global CDN distribution. We use Google Analytics for basic website usage statistics (anonymized, no personal data). All calculation code is client-side JavaScript—no backend processing of your sequences.
Limitations & Transparency
This is a tool website, not a comprehensive software suite. Commercial products like Primer3, OligoAnalyzer, or Geneious offer more features. I don't claim to replace them.
Individual developer means limited resources. Updates may be infrequent. Bug fixes prioritized over new features. No customer support team—just me responding to emails.
Use at your own risk. While calculations are verified against literature, I cannot guarantee error-free operation. Always validate critical designs independently.
Future Development
Planned improvements (no timeline promises):
- Mobile app (offline-capable PWA)
- Bulk sequence library management
- Advanced visualization options
- Export to vendor order formats
Development driven by user feedback and my available time. Open to contributions if this becomes an open-source project in the future.